A fat mass and obesity-associated gene polymorphism influences fat mass in exercise-trained individuals

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fat mass and obesity associated gene polymorphism and the risk of polycystic ovary syndrome: a meta-analysis

background: we aimed to elucidate the association between fat mass and obesity associated gene (fto) polymorphism and the risk of polycystic ovary syndrome (pcos) by meta-analysis. methods: we searched pubmed and embase databases to find the relevant studies. odds ratios (ors) and their corresponding 95% confidence intervals (cis) were used for pooled analysis. statistical analyses were carried...

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Fat Mass–and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity

OBJECTIVE To examine the longitudinal association of fat mass-and obesity-associated (FTO) variant with obesity, circulating adipokine levels, and FTO expression in various materials from human and mouse. RESEARCH DESIGN AND METHODS We genotyped rs9939609 in 2,287 men and 3,520 women from two prospective cohorts. Plasma adiponectin and leptin were measured in a subset of diabetic men (n = 854...

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Rs9939609 Variant of the Fat Mass and Obesity-Associated Gene and Trunk Obesity in Adolescents

A common T/A polymorphism (rs9939609) in the fat mass and obesity associated (FTO) gene was found associated with early-onset and severe obesity in both adults and children. However, recent observations failed to find associations of FTO with obesity. To investigate the genetic background of early obesity, we analysed the single nucleotide polymorphism (SNP) rs9939609 of FTO in 371 styrian adol...

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Association between rs9930506 polymorphism of the fat mass & obesity-associated (FTO) gene & onset of obesity in Polish adults

BACKGROUND & OBJECTIVES The fat mass and obesity-associated (FTO) gene is known to be associated with obesity. However, no data are available on the relation between FTO rs9930506 polymorphism and obesity in Polish population. The aim of this study was to evaluate an association between rs9930506 variants of the FTO gene and obesity in Polish adults. METHODS The study group consisted of 442 a...

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Emerging Function of Fat Mass and Obesity-Associated Protein (Fto)

Genome-wide association studies (GWAS) are a laborious but powerful tool to identify genetic risk factors associated with complex polygenic traits such as obesity [1], diabetes [2], or coronary artery disease [3]. The link between genetic variation in FTO and obesity was first described in a GWAS for type 2 diabetes [1] and was later independently confirmed in different populations all over the...

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ژورنال

عنوان ژورنال: Journal of the International Society of Sports Nutrition

سال: 2018

ISSN: 1550-2783

DOI: 10.1186/s12970-018-0246-7